"The big issue" ... ya think?

The big issue would be whether enough people felt that a chimp-Neanderthal hybrid would be acceptable, and that would be broadly discussed before anyone started to work on it.

-- Prof. George Church, on the possibility of mapping the Neanderthal genome and altering chimpanzee DNA to ultimately match the Neanderthal. A similar, though less potentially controversial, method is envisioned for using elephant DNA to recreate wooly mammoths.